Aviva Systems Biology's Hand2 antibody - C-terminal region (ARP30571_P050) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck